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Models

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Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3tm1(hAPOC3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225050
Validation Data：Presence

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

Mice

hCD40

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00076
Validation Data：Presence

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

Braf-Flox-V600E

Strain Name：C57BL/6Smoc-Brafem1(flox-V600E)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190053

These mice carry a conditional p.V600E mutation of Braf gene.

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190011
Validation Data：Presence

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

hC5

Strain Name：C57BL/6Smoc-Hctm1(hC5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000013
Validation Data：Presence

The endogenous mouse C5a gene was replaced by human C5 gene.

Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Il2rgem1Rag2em1Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220087

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000080
Validation Data：Presence

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

hC3

Strain Name：C57BL/6Smoc-C3tm1(hC3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000079
Validation Data：Presence

The endogenous mouse C3 gene was replaced by human C3 gene.

Mice

Csf1r-IRES-Cre

Strain Name：C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190026
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Csf1r gene stop codon site.

Mice

hCCR1

Strain Name：C57BL/6Smoc-Ccr1tm3(hCCR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190067

The endogenous mouse Ccr1 gene was replaced by human CCR1 gene.

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