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Models

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Mice

hCXCR2

Strain Name:C57BL/6Smoc-Cxcr2em2(hCXCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18025

The endogenous mouse Cxcr2 gene was replaced by human CXCR2 gene.

Mice

hIL12A

Strain Name:C57BL/6Smoc-Il12atm3(hIL12A)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000056

The endogenous mouse Il12a gene was replaced by human IL12A gene.

Mice

hPD-L1/hCD73(2)

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Nt5eem2(NT5E)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210356

hPD-L1(NM-HU-00062) was crossed with hCD73(2)(NM-HU-200009) to generate hPD-L1/hCD73(2) mice.

Mice

hPD-L1/hCD40

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd40em1(hCD40)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18024

hPD-L1(NM-HU-00062) was crossed with hCD40(NM-HU-00076) to generate hPD-L1/hCD40.

Mice

Axin2-CreERT2

Strain Name:C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200109

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

hPD-1/hLAG3

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00101

hPD-1(NM-HU-00015) was crossed with hLAG3(NM-HU-00049)to generate hPD-1/hLAG3 mice

Mice

hPVR

Strain Name:C57BL/6Smoc-Pvrtm1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190012

The endogenous mouse Pvr gene was replaced by human PVR gene.

Mice

hIL2/hIL2RA/hIL2RB/hIL2RG

Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210415

hIL2/hIL2RA(NM-HU-200275) was crossed with hIL2RA/hIL2RB/hIL2RG(NM-HU-210414) to generate hIL2/hIL2RA/hIL2RB/hIL2RG mice.

Mice

Dppa3-IRES-Cre

Strain Name:C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00040

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.

Mice

hIL23A

Strain Name:C57BL/6Smoc-Il23aem3(hIL23A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18030

The endogenous mouse Il23a gene was replaced by humanIL23A gene .

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