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Models

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Mice

Sdhb-Flox/Pgr-IRES-Cre(C57BL/6Smoc)

Strain Name:C57BL/6Smoc-Sdhbem1(flox)Pgrem1(IRES-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-XA-261365

The Sdhb-Flox (NM-CKO-226004) was crossed with Pgr-IRES-Cre(NM-KI-200150) to generate Sdhb-Flox/Pgr-IRES-Cre mice.

Mice

Hbb-bs-Flox/Prrx1-2A-CreERT2(C57BL/6Smoc)

Strain Name:C57BL/6Smoc-Hbb-bsem1(flox)Prrx1em(2A-CreERT2)1Smoc
Strain State:Developing | Cat. NO.:NM-XA-261354

The Hbb-bs-Flox (NM-CKO-241573) was crossed with Prrx1-2A-CreERT2(NM-KI-225017) to generate Hbb-bs-Flox/Prrx1-2A-CreERT2 mice.

Mice

Plp1-Flox

Strain Name:C57BL/6Smoc-Plp1em1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200072

These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene.

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name:C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200002
Validation Data:Presence  |  Publications:2piece

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

hPD-1

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00015
Validation Data:Presence  |  Publications:1piece

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

R26-CAG-LSL-RSR-tdTomato-2A-DTR

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-RSR-tdTomato-2A-DTR)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190086
Validation Data:Presence  |  Publications:2piece

These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

Mice

hPD-L1

Strain Name:C57BL/6Smoc-Cd274tm1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00062
Validation Data:Presence  |  Publications:1piece

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

hACE2

Strain Name:C57BL/6Smoc-Ace2tm3(hACE2-flag-Wpre-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200218
Validation Data:Presence  |  Publications:1piece

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

Mice

hCD81

Strain Name:C57BL/6Smoc-Cd81tm1(CD81)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

Mice

Kras-LSL-G12D

Strain Name:C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190003
Validation Data:Presence  |  Publications:2piece

exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

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