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Models

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Mice

Cav1-KO

Strain Name:C57BL/6Smoc-Cav1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190930

Exon 3 of Cav1 gene was deleted to generate Cav1 knockout mice.

Mice

Braf-Flox

Strain Name:C57BL/6Smoc-Brafem1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200073

These mice carry loxP sites flanking exon 5 of Braf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Braf gene.

Mice

hCD27(2)

Strain Name:C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190035

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093)have been pulled from shelves for some reasons.

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

Wnt5b-IRES-CreERT2-2A-tdTomato

Strain Name:C57BL/6Smoc-Wnt5bem(IRES-CreERT2-P2A-tdTomato)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215083

IRES-CreERT2-P2A-tdTomato expression cassette was knocked into the Wnt5b gene .

Mice

B2m-KO

Strain Name:C57BL/6Smoc-B2mem3Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18021

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200188

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hTIGIT

Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00053

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

hB7H4

Strain Name:C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hBTLA(2)

Strain Name:C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190040

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014)have been pulled from shelves for some reasons.

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