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Models

About 166 results
Mice

Rag2/Il2rg-KO/hSIRPA(BALB/c,2)

Strain Name：BALB/cAnSmoc-Sirpatm(hSIRPA)Rag2em1IL2rgem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234081

On the basis of strain hSIRPA(BALB/c,2), Rag2 and Il2rg gene exon3 and Il2rg gene exon2 were knocked out to establish Rag2 and IL2RG gene knockout mouse models in hSIRPA(BALB/c,2) background.

Mice

Rag2/IL2rg/Flt3-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Rag2em1IL2rgem1Flt3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-234080
Validation Data：Presence

In the background of Rag2/IL2rg-KO (BALB/c)(NM-KO-210231), the exon3 of Flt3 gene was knocked out to establish Rag2, IL2rg and Flt3 gene knockout mouse models.

Mice

hCD3EDG/Tnfrsf23-2A-TNFRSF10C(BALB/c)

Strain Name：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf23tm1(2A-TNFRSF10C-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-251881

Based on the hCD3EDG(BALB/c) NM-HU-220122 strain, the 2A-TNFRSF10C-WPRE-pA expression cassette was knocked into the Tnfrsf23 gene stop codon site.

Mice

Ccr8-P2A-DTR-2A-Luc(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8em(P2A-DTR-T2A-Luciferase)2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225088

P2A-DTR-T2A-Luciferase expression cassette was knocked into the Ccr8 gene .

Mice

R26-CAG-LSL-chPLA2R1-IRES-EGFP(BALB/c)

Strain Name：BALB/c-Gt(ROSA)26Sorem1(CAG-LSL-Kozak-chPLA2R1-IRES-EGFP-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-253775

CAG-LSL-Kozak-chPLA2R1-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.

Mice

Lepr-G/T(Intron17)(BALB/c)

Strain Name：BALB/cAnSmoc-Leprem(G/T)Smoc
Strain State：Developing | Cat. NO.：NM-KI-230478

G/T was knocked into exon19 of the Lepr gene(c.109052 G>T).

Mice

hCD40(BALB/c)

Strain Name：BALB/cAnSmoc-Cd40tm1(hCD40)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000047
Validation Data：Presence

The endogenous mouse Cd40 gene was replaced by human CD40 gene.

Mice

hLAG3(BALB/c)

Strain Name：BALB/cAnSmoc-Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000051

The endogenous mouse Lag3 gene was replaced by human LAG3 gene.

Mice

hSTING(BALB/c)

Strain Name：BALB/cAnSmoc-tmem173tm1(htmem173)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000049
Validation Data：Presence

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hIL1B(BALB/c)

Strain Name：BALB/cAnSmoc-Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220017
Validation Data：Presence

The endogenous mouse Il1b gene was replaced by human IL1B gene.

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