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Models

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Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200213

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

CD8a-IRES-Luc-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200208

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

BALB/c Nude

Strain Name:BALB/cAnSmoc-Foxn1nu/Smoc
Strain State:Repository Live | Cat. NO.:SM-014

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

Mice

hCCR8(BALB/c)(2)

Strain Name:BALB/cAnSmoc-Ccr8em(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220501

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

hCCR8(BALB/c)

Strain Name:BALB/cAnSmoc-Ccr8em1(hCCR8)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000048

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

hCD3EDG(BALB/c)

Strain Name:BALB/c-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Strain State:Repository Live | Cat. NO.:NM-HU-220122

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

Mice

hCD40/hCD40LG(BALB/c)

Strain Name:BALB/cAnSmoc-Cd40em(hCD40)Cd40lgtm(hCD40LG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220563

hCD40(BALB/c)(NM-HU-2000047)was crossed with hCD40L(BALB/c)(NM-HU-2000052to generate hCD40/hCD40LG(BALB/c).

Mice

Kit-KO(BALB/c)

Strain Name:BALB/cAnSmoc-Kitem2Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-232717

The exon3-4 of Kit gene was deleted to generate Kit knockout mouse.

Mice

hCD27/hPD-1(BALB/c)

Strain Name:BALB/cAnSmoc-Cd27tm(hCD27)Pdcd1em(hPD-1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220339

hCD27(BALB/c)(NM-HU-2000035) was crossed with hPD-1(BALB/c)(NM-HU-190079)to generate hCD27/hPDCD1(BALB/c).

Mice

hCD27/hPD-L1(BALB/c)

Strain Name:BALB/cAnSmoc-Cd27tm(hCD27)Cd274em(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220340

hCD27(BALB/c)(NM-HU-2000035) was crossed with hPD-L1(BALB/c)(NM-HU-220028)to generate hCD27/hPDCD1(BALB/c).

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