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Models

About 144 results
Mice

Il1rn-KO(BALB/c)

Strain Name:BALB/cAnSmoc-Il1rnem/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-230253

The exon 1-4 of Il1rn gene was deleted to generate Il1rn knockout mice.

Mice

hCTLA-4(BALB/c)

Strain Name:BALB/cAnSmoc-Ctla4em1(hCTLA4) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190078

Obtained by backcrossing of NM-HU-00014,hCTLA-4 mice.

Mice

Ighm/Ighd-KO(BALB/c)

Strain Name:BALB/cAnSmoc-Ighmem1Ighdem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210095

Exon 1-6 of Ighm and exon 1-5 of Ighd gene was deleted to generate Ighm and Ighd knockout mice.

Mice

Igkj-KO(BALB/c)

Strain Name:BALB/cAnSmoc-Igkjem4Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-200581

Igkj1, Igkj2, Igkj3, Igkj4, Igkj5, Igkc of Igkj gene was deleted to generate Igkj knockout mice.

Mice

hPD-1/hCTLA-4(BALB/c)

Strain Name:BALB/cAnSmoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200277

hPD-1(NM-HU-190079) was crossed with hCTLA4(2)(NM-HU-190078)to generate hPD-1/hCTLA4 mice

Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200213

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

CD8a-IRES-Luc-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200208

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

BALB/c Nude

Strain Name:BALB/cAnSmoc-Foxn1nu/Smoc
Strain State:Repository Live | Cat. NO.:SM-014

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

Mice

hCCR8(BALB/c)

Strain Name:BALB/cAnSmoc-Ccr8em1(hCCR8)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000048

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

hCD3EDG(BALB/c)

Strain Name:BALB/c-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Strain State:Repository Live | Cat. NO.:NM-HU-220122

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

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