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Mice

mB2m-hFCRN(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fcgrtem1(B2m-FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-018

A B2m-Linker-FCGRT-WPRE-polyA expression cassette was knocked into the Fcgrt gene exon3 of the NMG(NM-NSG-001) mice.

Mice

CAG-LSL-dCas9-SPH-Tg

Strain Name：C57BL/6Smoc-Tg(CAG-LSL-dCas9-SPH)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00025

Cre-dependent SunTag-p65-HSF1 (SPH) transgenic mice were generated with piggyBac transposon system in F1 zygotes and crossed with wild type C57BL/6 mice., SPH transgenic mouse containing HA-tagged dCas9 fused with 10xGCN4, which is linked with p65-HSF1 and EGFP in tandem via P2A and T2A respectively. The transgene is driven by the ubiquitous CAG promoter and interrupted by a loxP-stop-loxP (LSL) cassette to render Cas9 expression inducible by the Cre recombinase. Expression of dCas9 can be detected using primary antibody: rabbit monoclonal antibody to HA-tag (1:1000, #3724, CST45) and secondary antibody: goat anti-rabbit Alexa Fluor 488 (1:1000, #A-11034, Thermo Fisher).

Mice

Axl-KO

Strain Name：C57BL/6Smoc-Axlem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200044

Exon 3 of Axl gene was deleted to generate Axl knockout mice.

Mice

Avpr1a-KO

Strain Name：C57BL/6Smoc-Avpr1aem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200043

Exon 1-2 of Avpr1a gene was deleted to generate Avpr1a knockout mice.

Mice

A4galt-KO

Strain Name：C57BL/6Smoc-A4galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

Mice

Apoa2-KO

Strain Name：C57BL/6Smoc-Apoa2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200035

Exon 3 of Apoa2 gene was deleted to generate Apoa2 knockout mice.

Mice

Tyro3-KO

Strain Name：C57BL/6Smoc-Tyro3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200558

Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice.

Mice

Mc4r-KO

Strain Name：C57BL/6Smoc-Mc4rem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200357

Exon 1 of Mc4r gene was deleted to generate Mc4r knockout mice.

Mice

Aak1-KO

Strain Name：C57BL/6Smoc-Aak1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200002

Exon 3 of Aak1 gene was deleted to generate Aak1 knockout mice.

Mice

Mertk-KO

Strain Name：C57BL/6Smoc-Mertkem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200362

Exon 2 of Mertk gene was deleted to generate Mertk knockout mice.

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