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Research on Diseases

genetics diseases studies diseases research diseases

Shanghai Model Organisms provides a professional R&D platform for genetically-engineered mouse, zebrafish and nematode models, a service platform for phenotyping, and a rich repository of disease mouse models to support your studies on disease genetics, pathogenesis, drug treatments, and more.

GEMM-Derived Allografts

Osteoporosis

osteoporosis gene osteoporosis diseases Tnfrsf11b

Tnfrsf11b (Opg) knockout mice were generated through homologous recombination and supplied by Shanghai Research Center for Model Organisms. This mouse model, which is referred to as the "osteoporotic mouse", shows a typical phenotype of osteoporosis and arterial calcification, and Therefore, this animal model is ideal for drug screening and evaluation for the treatment of "human osteoporosis", in gene therapy of osteoporosis, as well as in the research on the mechanisms of interaction between osteoclasts and osteoblasts.

Customize your genetically engineered models

knockout mouse transgenic mouse transgenic mouse models

The scientific team at Shanghai Model Organisms Center, Inc, comprising of seasoned molecular biologists and technicians, is dedicated to providing highly customizable, genetically engineered models to global researchers.

Gene Knockout

gene knockout gene knockout technology knockout mice

Expedite your research with highly customizable, gene knockout mouse models that provide thorough insight into key genetic mechanisms.

Housing and Management

More than 20 years of professional barrier facility management and operation and maintenance experience.

飼育管理

専門的な動物飼育室の管理と、運営とメンテナンスに関するの経験を２０年間持っており、専門的な動物飼育室の代行管理業務を提供することができます。　

사육 관리

20년 이상의 전문 동물실 관리 및 운영 경험을 기반으로, 전문적인 동물실 관리 업무를 제공합니다.

Behavioral Analysis

study of animal behavior behavioral analysis

Shanghai Model Organisms' rodent behavioral analysis platform is equipped with a variety of experimental instruments used to study the classical behaviors of mice. Shanghai Model Organisms can provide single-item or complete sets of mouse behavioral analysis to assist you with your research in neurology, physiology, drug development, and drug efficacy evaluation. The Noldus behavioral analysis system is used to more comprehensively and accurately reflect the neurological and mental states of mice.

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