Welcome to Advanced Search

Terms of Shipping

Please read our Terms of Shipping to understand the issues that may arise during transportation of the animals.

Resources & Support

resource center support center

Obtain our product brochures, view our past publications, download animal health reports, browse products and literature, explore a variety of common issues, and get online support from our technical experts.

Disease Mouse Models (Non-genetically-engineered)

diseases mice diseases model non genetically modified organisms

Shanghai Model Organisms has established a library of typical mouse models of human diseases through surgery or drug induction, thereby providing useful animal models for the research on pathogenesis of related diseases, functional studies of genes or proteins in diseases, screening of disease drugs and evaluation of therapeutic effects, etc.

Osteoporosis

osteoporosis gene osteoporosis diseases Tnfrsf11b

Tnfrsf11b (Opg) knockout mice were generated through homologous recombination and supplied by Shanghai Research Center for Model Organisms. This mouse model, which is referred to as the "osteoporotic mouse", shows a typical phenotype of osteoporosis and arterial calcification, and Therefore, this animal model is ideal for drug screening and evaluation for the treatment of "human osteoporosis", in gene therapy of osteoporosis, as well as in the research on the mechanisms of interaction between osteoclasts and osteoblasts.

Popular Model Organisms

genetically modified organisms transgenic organisms genetically modified organisms examples

Model organisms are instrumental to the study of gene functions. Gene editing technology has always played a crucial role in the research on gene functions, diseases and drug discovery, through its application in genetic engineering of model organisms, mimicking of human diseases, as well as observation of physiological or pathological changes. In particular, the CRISPR/Cas9 technology has achieved remarkable breakthroughs in recent years, significantly improving the efficiency of genetic engineering in model organisms, and facilitating more extensive and in-depth applications of animal models in various research fields.

Drug Screening

drug screening high throughput screening for drug discovery

With a comprehensive model organisms service platform that generates the mouse, zebrafish and C. elegans models, Shanghai Model Organisms enables high-throughput drug screening as well as the evaluation and research on drug efficacy, thus accelerating drug development and achieving greater accuracy in the prediction of in vivo interactions.

Breeding Services

We will delivery the specific genotype model product within specific period by natural breeding or assisted reproduction technology. The specified breeding technologies include natural breeding, assisted reproduction, SPF purification, etc.

モデルマウスの繁殖

カスタマイズされた後のモデル、またはお客様の既有の遺伝子組み換え動物モデルは、自然繁殖または補助的生殖繁殖の方法によって、特定周期に、特定遺伝子型モデル製品として提供されます。具体的には、自然繁殖、補助的生殖繁殖、 SPF精製等が含まれます。

모델 번식

특정 유전자 조합 모델 상품을 자연 번식 혹은 보조 생식하여 특정 시기에 납품됩니다. 이미 고객님이 보유한 유전자 변형 동물 모델 또한 자연 번식 혹은 보조 생식 서비스를 제공합니다.구체적 번식 기술: 자연 번식, 보조 생식, SPF 정화 등.

Who We are