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How do I establish a strain after the transgenic Founder mice are obtained?

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Type of genetic engineering

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Three types of genetic modification by the gene engineered technology: gene knockout. gene knock-in, gene overexpression.

Overview of gene editing technology

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Customize your genetically engineered models

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The scientific team at Shanghai Model Organisms Center, Inc, comprising of seasoned molecular biologists and technicians, is dedicated to providing highly customizable, genetically engineered models to global researchers.

Mouse

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Mice have long been the prime choice for model organisms. In more than 100 years, mice have been widely used by researchers in the fields of physiology, pathology, pharmacology, toxicology, and behavioral science. With the establishment of gene targeting technology, many researchers have made their way to the Nobel Prize.

Study of Gene Functions

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Why We Need Humanized Mice?

Customization of MIT Alpaca Recombinant mAb

Lineage tracing

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Genetic lineage tracing is a commonly used and the most effective method for studying the origin and fate of specific cell types. The construction of genetically engineered mouse model is the most important step in the lineage tracing technique.

Some Basics about Cre-lox and Inducible Cre in Mouse Modeling