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Lep-KO(SD)

Strain Name：SD-Lep^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-200001

Exon 2-3 of Lep gene was deleted to generate Lep knockout rat.

LNCaP clone FGC

Strain Name：LNCaP clone FGC
Strain State ： Validation of tumorigenic capacity completed |  Cat. NO.：NM-Q03

LNCaP clone FGC is a cell line exhibiting epithelial morphology that was isolated in 1977 by J.S. Horoszewicz, et al., from a needle aspiration biopsy of the left supraclavicular lymph node of a 50-year-old, White, male (blood type B+) with confirmed diagnosis of metastatic prostate carcinoma.

Harnessing the Power of the Cre-loxP System: Benefits, Challenges, and Applications

This webinar will introduce the Cre-loxP system, a powerful genetic tool that has revolutionized biological research by allowing for conditional gene knockout, knockdown, and overexpression. We will cover the history of the genetic recombination systems, discuss how they enable precise control of gene expression in specific cell types or at specific developmental stages, and present GenoBioTX’s genetically modified models utilizing this method.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

What is the reason to use sentinel mice?

sentinel mice BALB/c mice C57BL/6 mice

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

Bone metastasis cancer model Pain-related behavior assessment Cancer-induced bone pain Bone cancer pain models Mouse bone metastasis model Animal models in cancer research Cancer research services Bone metastasis in mice Pain management in cancer

We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

How do I identify the genotypes of genetically-engineered mice?

genomic DNA PCR gel electrophoresis

Genotyping method for CRISPR/Cas9 point mutation mouse

Genotyping method for CRISPR/Cas9 Knockout mouse

How do I breed conventional knockout mice or genetically mutated mice? How do I choose control mice for experiments?

genetically mutated neo gene phenotype definition