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Rats

hFcRn(SD)

Strain Name:SD-Fcgrtem1(hFCGRT)Smoc Strain State:Repository Live | Cat. NO.:NR-HU-200002

The endogenous rat Fcgrt gene was replaced by human FCGRT gene.

Rats

Ahr-KO(SD)

Strain Name:SD-Ahrem1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-200005

Exon 2 of Ahr gene was deleted to generate Ahr knockout rat.

Rats

Slc22a1-KO(SD)

Strain Name:SD-Slc22a1em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190009

Exon 2-3 of Slc22a1(Oct1) gene was deleted to generate Slc22a1(Oct1) knockout rat.

Rats

Nr1i3-KO(SD)

Strain Name:SD-Nr1i3em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190008

Exon 2 of Nr1i3 gene was deleted to generate Nr1i3 knockout rat.

Rats

Abcc2-KO(SD)

Strain Name:SD-Abcc2em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-200002

Exon 4-6 of Abcc2 gene was deleted to generate Abcc2 knockout rat.

Rats

Abcg2-KO(SD)

Strain Name:SD-Abcg2em1Smoc Strain State:Repository Live | Cat. NO.:NR-KO-190007

Exon 4-5 of Abcg2 gene was deleted to generate Abcg2 knockout rat.

Pages

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

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These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

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Join Our Webinar: Applications of Humanized Mouse Models in Preclinical Research

Humanized mouse models preclinical research targeted therapies webinar oncology drug development preclinical therapeutic advancements immune system models animal modeling services

Join GenoBioTX's webinar on July 25th to explore the latest advancements in humanized mouse models for preclinical research. Learn how these models are transforming targeted therapy development across various diseases. Featuring expert insights from Dr. Derek Reznik, discover the generation and application of humanized immune system models in oncology drug development. Don't miss this opportunity to enhance your knowledge in cutting-edge preclinical therapeutic advancements. Register now!

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Advancing Cancer Therapy: Harnessing In Vivo Tumor Models for Breakthrough Drug Development

Cancer therapy advancements In vivo tumor models Preclinical cancer research Drug development in oncology Gene-modified cell lines Immuno-oncology Tumor modeling for drug discovery Cancer drug development Animal modeling services Cancer drug preclinical models

Join us for an insightful webinar exploring the critical role of in vivo tumor models in advancing cancer drug therapy. We will provide an overview of the diverse tumor models developed by our company, highlighting case studies demonstrating their effectiveness in preclinical cancer research. The session will delve into the comprehensive use of gene-modified cell lines and genetically modified spontaneous mouse models, showcasing their application in mimicking human cancer biology. We will conclude with a brief introduction to our company and our commitment to accelerating cancer drug development through innovative animal modeling services.

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