Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:SD-Fcgrtem1(hFCGRT)Smoc Strain State:Repository Live | Cat. NO.:NR-HU-200002
The endogenous rat Fcgrt gene was replaced by human FCGRT gene.
Strain Name:SD-Ahrem1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-200005
Exon 2 of Ahr gene was deleted to generate Ahr knockout rat.
Strain Name:SD-Slc22a1em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190009
Exon 2-3 of Slc22a1(Oct1) gene was deleted to generate Slc22a1(Oct1) knockout rat.
Strain Name:SD-Nr1i3em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190008
Exon 2 of Nr1i3 gene was deleted to generate Nr1i3 knockout rat.
Strain Name:SD-Abcc2em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-200002
Exon 4-6 of Abcc2 gene was deleted to generate Abcc2 knockout rat.
Strain Name:SD-Abcg2em1Smoc Strain State:Repository Live | Cat. NO.:NR-KO-190007
Exon 4-5 of Abcg2 gene was deleted to generate Abcg2 knockout rat.
U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.
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The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.
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Join GenoBioTX's webinar on July 25th to explore the latest advancements in humanized mouse models for preclinical research. Learn how these models are transforming targeted therapy development across various diseases. Featuring expert insights from Dr. Derek Reznik, discover the generation and application of humanized immune system models in oncology drug development. Don't miss this opportunity to enhance your knowledge in cutting-edge preclinical therapeutic advancements. Register now!
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Join us for an insightful webinar exploring the critical role of in vivo tumor models in advancing cancer drug therapy. We will provide an overview of the diverse tumor models developed by our company, highlighting case studies demonstrating their effectiveness in preclinical cancer research. The session will delve into the comprehensive use of gene-modified cell lines and genetically modified spontaneous mouse models, showcasing their application in mimicking human cancer biology. We will conclude with a brief introduction to our company and our commitment to accelerating cancer drug development through innovative animal modeling services.
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