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Models

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Mice

Dicer1-Flox

Strain Name：C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200158

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

Casr-Flox

Strain Name：C57BL/6Smoc-Casrem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200085

These mice carry loxP sites flanking exon 3 of Casr gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Casr gene.

Mice

Ppard-Flox

Strain Name：C57BL/6Smoc-Ppardtm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-190068

These mice carry loxP sites flanking exon 4 of Ppard gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ppard gene.

Mice

Wnt11-Flox

Strain Name：C57BL/6Smoc-Wnt11em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200146

These mice carry loxP sites flanking exon 4 of Wnt11 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Wnt11 gene.

Mice

B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-002

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.  These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

R26-CAG-LSL-hBCR/ABL

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190127

These mice harbor a CAG-LSL-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Wrn-KO

Strain Name：C57BL/6Smoc-Wrnem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190902

Exon 5-8 of Wrn gene was deleted to generate Wrn knockout mice.

Mice

Cth-Luc

Strain Name：B6;129S-Cthtm1(Luc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00004

Cth was targeted by insertion of a floxed Luciferase gene and an frt-neo-frt cassette before exon 1. These mice have normal development and fertility.

Mice

Vpreb1-KO

Strain Name：C57BL/6Smoc-Vpreb1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200688

Exon 1-2 of Vpreb1 gene was deleted to generate Vpreb1 knockout mice.

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