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Models

About 598 results
Mice

hPD-1

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00015

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

Ambra1-Flox

Strain Name：C57BL/6Smoc-Ambra1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200059

These mice carry loxP sites flanking exon4 of Ambra1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ambra1 gene.

Mice

hPD-L1

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

h4-1BB(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190077

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099）have been pulled from shelves for some reasons.

Mice

h4-1BBL

Strain Name：C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00048

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

Arg1-KO

Strain Name：C57BL/6Smoc-Arg1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200629

Exon 3 of Arg1 gene was deleted to generate Arg1 knockout mice.

Mice

hHER2

Strain Name：C57BL/6Smoc-Erbb2tm1(hERBB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200115

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

Mice

Cldn16-KO

Strain Name：C57BL/6Smoc-Cldn16em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200632

Exon 2 of Cldn16 gene was deleted to generate Cldn16 knockout mice.

Mice

Arg1-Flox

Strain Name：C57BL/6Smoc-Arg1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200062

These mice carry loxP sites flanking exon 5-8 of Arg1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Arg1 gene.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

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