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Models

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Mice

hHER2

Strain Name：C57BL/6Smoc-Erbb2tm1(hERBB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200115

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

Mice

Arg1-KO

Strain Name：C57BL/6Smoc-Arg1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200629

Exon 3 of Arg1 gene was deleted to generate Arg1 knockout mice.

Mice

Cldn16-KO

Strain Name：C57BL/6Smoc-Cldn16em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200632

Exon 2 of Cldn16 gene was deleted to generate Cldn16 knockout mice.

Mice

Arg1-Flox

Strain Name：C57BL/6Smoc-Arg1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200062

These mice carry loxP sites flanking exon 5-8 of Arg1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Arg1 gene.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

Foxp1-Flox

Strain Name：C57BL/6Smoc-Foxp1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200168

These mice carry loxP sites flanking exon 6-7 of Foxp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Foxp1 gene.

Mice

Resp18-KO

Strain Name：B6;129S-Resp18tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00022

These Resp18 knockout mice were established technology and crossed with FLP transgenic mice to delete PGK-Neo gene.

Mice

R26-CAG-LSL-hWNT1

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190128

These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-WNT1-IRES-Luc-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Nfe2l2-Flox

Strain Name：C57BL/6Smoc-Nfe2l2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200198

These mice carry loxP sites flanking exon 5 of Nfe2l2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nfe2l2 gene.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

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