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Models

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Mice

hTIGIT

Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00053

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

Taz-Flox

Strain Name:C57BL/6Smoc-Tazem2(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200001

These mice carry loxP sites flanking exon5-10 of Taz gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Taz gene.

Mice

hVISTA

Strain Name:C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00118

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

hSTING

Strain Name:C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190036

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hOX40

Strain Name:C57BL/6Smoc-Tnfrsf4em1(hTNFRSF4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00041

The endogenous mouse Tnfrsf4(Ox40) gene was replaced by human TNFRSF4(OX40) gene. While hOX40(2)(Stock No.NM-HU-00078) mice function similarly to hOX40 mice,for more detailed information please contact our technical advisor.

Mice

hB7H4(2)

Strain Name:C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

hLAG3

Strain Name:B6.129S-Lag3tm1(hLAG3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00049

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hCD160

Strain Name:C57BL/6Smoc-Cd160em1(CD160)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190057

The endogenous mouse Cd160 gene was replaced by human CD160 gene.

Mice

hSEMA4D

Strain Name:C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00117

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

Mice

hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00100

hPD-1(NM-HU-00015) was crossed with hPD-L1(NM-HU-00062)to generate hPD-1/hPD-L1 mice

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