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Models

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Mice

Lats2-Flox

Strain Name：C57BL/6Smoc-Lats2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200010

These mice carry loxP sites flanking exon 4 of Lats2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lats2 gene.

Mice

Fah-KO

Strain Name：C57BL/6Smoc-Fahem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191202

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

Mice

Btd-KO

Strain Name：C57BL/6Smoc-Btdem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200630

Exon 2-3 of Btd gene was deleted to generate Btd knockout mice.

Mice

4-1BB-KO

Strain Name：C57BL/6Smoc-Tnfrsf9em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00088

Exon2 of Tnfrsf9 (4-1BB) gene was deleted to generate Tnfrsf9 (4-1BB) knockout mice.

Mice

H11-CAG-LSL-hACHE

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-ACHE-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00067

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ACHE gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. ACHE is expressed when bred to mice that express Cre recombinase.

Mice

Tnf-KO

Strain Name：C57BL/6Smoc-Tnfem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00100

Exon2-3 of Tnf gene were targeted to generate the Tnf knockout mice.

Mice

Hdac6-KO

Strain Name：C57BL/6Smoc-Hdac6em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18009

Exon11-14 of Hdac6 gene were deleted to generate Hdac6 knockout mice.

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

Dmd-KO

Strain Name：C57BL/6Smoc-Dmdem3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200573

Exon 52 of Dmd gene was deleted to generate Dmd knockout mice.

Mice

hACE2

Strain Name：C57BL/6Smoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200218

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

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