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Models

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Mice

Ces1c-Flox

Strain Name：C57BL/6Smoc-Ces1cem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200152

These mice carry loxP sites flanking exon 5 of Ces1c gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ces1c gene.

Mice

Cdkn1b-KO

Strain Name：C57BL/6Smoc-Cdkn1bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200622

Exon 1-2 of Cdkn1b gene was deleted to generate Cdkn1b knockout mice.

Mice

Cyp2e1-CreERT2

Strain Name：C57BL/6Smoc-Cyp2e1em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-00047

A kozak-CreERT2-Wpre-polyA cassette was inserted at ATG site of Cyp2e1 gene via CRISPR/Cas mediated recombination.

Mice

Pex1-Flox

Strain Name：C57BL/6Smoc-Pex1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200205

These mice carry loxP sites flanking exon 12-13 of Pex1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pex1 gene.

Mice

Magi3-KO

Strain Name：C57BL/6Smoc-Magi3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200620

exon4-5 of Magi3 gene was deleted to generate Magi3 knockout mice.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

hACE2

Strain Name：C57BL/6Smoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200218

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200188

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Aldob-KO

Strain Name：C57BL/6Smoc-Aldobem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200602

Exon 3-6 of Aldob gene was deleted to generate Aldob knockout mice.

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