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Models

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Mice

Trp53-LSL-R270H

Strain Name：C57BL/6Smoc-Trp53tm7(R270H-flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200186

These mice carry a p.R270H conditional mutation of Trp53 gene.

Mice

Hltf-Flox

Strain Name：C57BL/6Smoc-Hltfem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200037

These mice carry loxP sites flanking exon 3 of Hltf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hltf gene.

Mice

Xpc-KO

Strain Name：C57BL/6Smoc-Xpcem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200589

Exon 3 of Xpc gene was deleted to generate Xpc knockout mice.

Mice

Ldlr-KO

Strain Name：C57BL/6Smoc-Ldlrem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190559

Ldlr-KO mice(Stock No.NM-KO-190559) carry a knockout allele derived from the targeted deletion of exon 6-10. While Ldlr-KO(2) mice(Stock No.NM-KO-210198) carrying the exon 4 deletion.

Mice

Tet2-KO

Strain Name：B6;129S-Tet2tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00127

Exon3 of mouse Tet2 gene was replaced by frt-Pgk-Neo-polyA-frt cassette by homologous recombination.

Mice

R26-CAG-LSL-hRHOA*Y42C-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200048

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18052

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

Mice

Becn1-Flox

Strain Name：C57BL/6Smoc-Becn1tm1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-18008

These Becn1 flox mice possess loxP sites flanking exons 3 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Akap12-KO

Strain Name：C57BL/6Smoc-Akap12em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200609

Exon 3 of Akap12 gene was deleted to generate Akap12 knockout mice.

Mice

R26-LSL-hEZH2-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18053

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.

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