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Models

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Mice

Fzd5-Flox

Strain Name:C57BL/6Smoc-Fzd5tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200178

These mice carry loxP sites flanking exon 2 of Fzd5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Fzd5 gene.

Mice

Kras-LSL-G12D

Strain Name:C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190003

exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

Mice

hB7H3

Strain Name:C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00107

The endogenous mouse Cd276 gene was replaced by human CD276 gene.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name:C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hCD40

Strain Name:C57BL/6Smoc-Cd40em1(hCD40) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00076

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

Pten-KO

Strain Name:C57BL/6Smoc-Ptenem3Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

hCTLA-4

Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00014

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

Braf-Flox-V600E

Strain Name:C57BL/6Smoc-Brafem1(flox-V600E)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190053

These mice carry a conditional p.V600E mutation of Braf gene.

Mice

hPD-L1/hCD28

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

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