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Models

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Mice

BALB/c Nude

Strain Name:BALB/cAnSmoc-Foxn1nu/Smoc
Strain State:Repository Live | Cat. NO.:SM-014

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

Mice

R26-CAG-FLEX-Zbp1-Mouse-L-3xFLAG

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-250273

The CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

R26-CAG-LSL-Zbp1-Mouse-L-3xFLAG-bGH

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Kozak-Zbp1-Mouse-L-3xFLAG-WPRE-bGH-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-241596

The CAG-LSL-Kozak-Zbp1-Mouse-L-3xFLAG-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

Ncr1-2A-Cre

Strain Name:C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190027

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Ncr1-IRES-mtagBFP2-Luc

Strain Name:C57BL/6Smoc-Ncr1em5(IRES-mtagBFP-luciferase)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200030

A IRES-mtagBFP-luciferase expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

HLA-A2.1/B2M(NMG)(2)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*0201/H2-D1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-241683

The endogenous mouse B2m gene was replaced by hB2M/HLA-A2.1/H2-D1 gene.

Mice

hXDH(2)

Strain Name:C57BL/6Smoc-Xdhtm2(hXDH)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-240110

The endogenous mouse Xdh gene was replaced by human XDH gene.

Mice

hEBI3

Strain Name:C57BL/6Smoc-Ebi3tm1(hEBI3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234509

The endogenous mouse Ebi3 gene was replaced by human EBI3 gene.

Mice

hNR1H2

Strain Name:C57BL/6Smoc-Nr1h2em1(hNR1H2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234706

The endogenous mouse Nr1h2 gene was replaced by human NR1H2 gene.

Mice

hC3

Strain Name:C57BL/6Smoc-C3em1(hC3)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000079

The endogenous mouse C3 gene was replaced by human C3 gene.

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