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Models

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Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220011

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

hIL17RA

Strain Name：C57BL/6Smoc-Il17ratm1(hIL17RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190049

The endogenous mouse Il17ra gene was replaced by human IL17RA gene.

Mice

hLAIR1

Strain Name：C57BL/6Smoc-Lair1em2(LAIR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000011

The endogenous mouse Lair1 gene was replaced by human LAIR1 gene .

Mice

hIL4

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190071

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

hPD-L1

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

h4-1BB(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190077

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099）have been pulled from shelves for some reasons.

Mice

h4-1BBL

Strain Name：C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00048

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

Sirpa-Nod

Strain Name：C57BL/6Smoc-Sirpaem1(Sirpa-Nod)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232215

All coding sequences of C57 mouse gene exon3 were replaced with all coding sequences of Nod mouse gene exon3.

Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

hCD20(2)

Strain Name：C57BL/6Smoc-Ms4a1tm2 (hCD20)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200114

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

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