Welcome to Advanced Search

Models

About 3,264 results
Mice

hIL33

Strain Name：C57BL/6Smoc-Il33tm2(hIL33)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000069

The endogenous mouse Il33 gene was replaced by human IL33 gene.

Mice

hTHPO

Strain Name：C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000062

The endogenous mouse Thpo gene was replaced by human THPO gene.

Mice

hIL10

Strain Name：C57BL/6Smoc-Il10tm4(hIL10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000063

The endogenous mouse Il10 gene was replaced by human IL10 gene.

Mice

hIL1RAP

Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000070

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

Mice

hNR1I2

Strain Name：C57BL/6Smoc-Nr1i2em3(hNR1I2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000066

The endogenous mouse Nr1i2 gene was replaced by human NR1I2 gene.

Mice

hIL1RL1

Strain Name：C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000067

The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.

Mice

R26-LSL-Notch1C-IRES-nEGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Notch1C-IRES-nEGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200036

These mice harbor a SA-LSL-Notch1C-IRES-nEGFP cassette in the Rosa26 locus generated by homologous recombination.Notch1C (mouse Notch1 ,amino acids 1749–2293)

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

MHCII/B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

Email Back to top