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Models

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Mice

hCTLA-4/4-1BB

Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18020

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

B2m-KO(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Strain State:Repository Live | Cat. NO.:NM-NSG-002

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

Hc-KO

Strain Name:C57BL/6Smoc-Hcem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190191

This Hc knockout mouse model was generated by knocking out the exon 6 region of the Hc.

Mice

Fcgr1-KO

Strain Name:C57BL/6Smoc-Fcgr1em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

Alpl-KO

Strain Name:C57BL/6Smoc-Alpltm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18058

This Alpl knockout mouse model was obtained by knocking out the exon 3-4 region of the Alpl gene.

Mice

Cd200-KO

Strain Name:C57BL/6Smoc-Cd200em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

Drd2-KO

Strain Name:C57BL/6Smoc-Drd2em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190265

This Drd2 knockout mouse model was generated by knocking out the exon 3 region of the Drd2.

Mice

Ifnar1-KO

Strain Name:C57BL/6Smoc-Ifnar1em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18038

The Ifnar1 knockout mouse model was obtained by knocking out the exon 3-11 region of mouse Ifnar1 gene.

Mice

1300017j02Rik-KO

Strain Name:C57BL/6Smoc-1300017j02Rikem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190231

This 1300017j02Rik knockout mouse model was generated by knocking out the exon2-12 region of the 1300017j02Rik.

Mice

Snca-KO

Strain Name:C57BL/6Smoc-Sncaem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190380

This Snca knockout mouse model was generated by knocking out the exon4 region of the Snca.

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