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Models

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Mice

Trap1-K128R

Strain Name:C57BL/6Smoc-Trap1em1(K128R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210090

These mice carry a K128R mutation of Trap1 gene.

Mice

R26-CAG-LSL-Mettl3-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-3xFLAG-Mettl3-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190056

These mice harbor a CAG-LSL-3xFLAG-Mettl3-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

Reg4-IRES-FLP

Strain Name:C57BL/6Smoc-Reg4em1(IRES-FLP-Wpre-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200309

IRES-FLP-Wpre-pA expression cassette was knocked into the Reg4 gene stop codon site.

Mice

hOX40/hCTLA-4

Strain Name:C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCD19/hCD3E

Strain Name:C57BL/6Smoc-Cd19em1(hCD19)Cd3eem1(hCD3E)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190027

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hTLR9/hOX40

Strain Name:C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL6/hIL6R

Strain Name:C57BL/6Smoc-Il6tm1(hIL6)Il6raem1(hIL6R)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190025

This IL6 and IL6R double knockin strain is established by crossing IL6-HU and IL6R-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hICOS/hICOSL

Strain Name:C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18018

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hLAG3/hCTLA-4

Strain Name:B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190018

This LAG3 and CTLA4 double knockin strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCTLA-4/4-1BB

Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18020

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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