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Models

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Mice

Krt14-2A-DreERT2

Strain Name：C57BL/6Smoc-Krt14em3(2A-DreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190125

A 2A-DreERT2 expression cassette was knocked into the Krt14 gene stop codon site.

Mice

Tnni3-dCreERT2

Strain Name：C57BL/6Smoc-Tnni3em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200014

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnni3 gene start codon site.

Mice

Zap70-W163C(Balb/c)

Strain Name：BALB/cAnSmoc-Zap70em(W163C)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210366

These mice carry a W163C mutation of Zap70 gene.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

Ncr1-2A-Cre

Strain Name：C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190027

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Ncr1-IRES-mtagBFP2-Luc

Strain Name：C57BL/6Smoc-Ncr1em5(IRES-mtagBFP-luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200030

A IRES-mtagBFP-luciferase expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

R26-LSL-Notch1C-IRES-nEGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Notch1C-IRES-nEGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200036

These mice harbor a SA-LSL-Notch1C-IRES-nEGFP cassette in the Rosa26 locus generated by homologous recombination.Notch1C (mouse Notch1 ,amino acids 1749–2293)

Mice

R26-LSL-SmoM2W539L-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200035

These mice harbor a SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. W539L point mutation of the mouse gene (SmoM2), which corresponds to the W535L mutation in the human sequence.

Mice

Etv1-CreERT2

Strain Name：C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

R26-CAG-LSL-zsGreen

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-zsGreen)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200045

These mice harbor a CAG-LSL-zsGreen-polyA cassette in the Rosa26 locus generated by homologous recombination.

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