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Models

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Mice

R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190067

These mice harbor a CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

hSIRPA(2)/hCD47/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095

hPD-L1(NM-HU-00062),hCD47(NM-HU-00050) was crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-L1.

Mice

R26-CAG-LSL-hFGFR3*S249C-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR3(S249C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190082

These mice harbor a CAG-LSL-FGFR3(S249C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-emL4-ALK-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190072

These mice harbor a CAG-LSL-EML4-ALK-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.Please check if the EML4-ALK fusion variant is what you need before ordering.

Mice

hPD-1/hICOS(2)

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Icosem1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000100

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Mice

Sox2-CreERT2

Strain Name：C57BL/6Smoc-Sox2em1(CreERT2-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200084

The coding region of Sox2 gene was replaced by a CreERT2-polyA expression cassette.

Mice

R26-CAG-LSL-hNFE2L2*G81S-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190077

These mice harbor a CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Opn4-Cre

Strain Name：C57BL/6Smoc-Opn4em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200304

Cre-WPRE-polyA expression cassette was knocked into the Opn4 gene start codon site. The melanopsin gene (Opn4) encodes a functional photopigment. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying circadian rhythm regulation.

Mice

KPC(2)

Strain Name：C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220014

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

R26-CAG-LSL-hTARDBP*A315T-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200019

These mice harbor a CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

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