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Models

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Mice

Notch1-CreERT2

Strain Name：C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200122

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

Cdh6-CreERT2

Strain Name：C57BL/6Smoc-Cdh6em1(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200140

A CreERT2-WPRE-polyA expression cassette was knocked into the Cdh6 gene start codon site.

Mice

R26-pAlb-TK-IRES-Luc-2A-EGFP(NOD-scid)

Strain Name：NOD-PrkdcscidGt(ROSA)26Sorem1(Alb-TK-IRES-luc-2A-EGFP-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18040

These Nod-Scid mice harbor a cassette containing Alb promoter-TK-IRES-luciferase-2A-EGFP-polyA. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

Il13-IRES-Cre

Strain Name：C57BL/6Smoc-Il13em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200166

A IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process.

Mice

R26-SA-LSL-DTR-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-DTR-IRES-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210136

A SA-LSL-DTR-IRES-tdTomato expression cassette was knocked into via the Rosa26 locus.

Mice

Slc17a6-IRES-Cre

Strain Name：C57BL/6Smoc-Slc17a6em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200087

A IRES-iCre expression cassette was knocked into the Slc17a6 gene stop codon site.

Mice

Col1a2-2A-Cre

Strain Name：C57BL/6Smoc-Col1a2em1(2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215043

2A-Cre expression cassette was knocked into the Col1a2 gene.

Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

Mice

Myh11-2A-DreERT2

Strain Name：C57BL/6Smoc-Myh11em1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190037

A 2A-DreERT2 expression cassette was knocked into the Myh11 gene stop codon site.

Mice

Pgr-Cre

Strain Name：C57BL/6Smoc-Pgrem1(iCre-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200117

A iCre-WPRE-pA expression cassette was knocked into the Pgr gene start codon site.

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