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Mice

Myf5-Cre

Strain Name:C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200147

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Mc4r-2A-Cre

Strain Name:C57BL/6Smoc-Mc4rem1(T2A-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200220

A T2A-Cre expression cassette was knocked into the Mc4r gene stop codon site.

Mice

Agr2-2A-CreERT2(2)

Strain Name:C57BL/6Smoc-Agr2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-231956

The 2A-CreERT2-WPRE-pA expression cassette was knocked into the Agr2 gene stop codon site.

Mice

Ifng-Venus-Luc

Strain Name:C57BL/6Smoc-Ifngem1(IRES-Venus-Luci)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18041

An IRES-Venus-Luci co-expression cassette was inserted in 3'UTR region of Ifng gene.

Mice

Calb1-2A-GFPCre

Strain Name:C57BL/6Smoc-Calb1em1(2A-EGFP-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200141

A 2A-EGFP-Cre expression cassette was knocked into the Calb1 gene stop codon site. Calb1 is highly expressed in the brain. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful in studying many neurobehavioral diseases such as spatial learning and circadian rhythm interference. It has been reported that the incidence of many diseases may be different between genders.

Mice

Crh-IRES-Cre

Strain Name:C57BL/6Smoc-Crhem1(IRES-iCre-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200104

A IRES-iCre-pA expression cassette was knocked into the Crh gene stop codon site. This strain exhibits ectopic expression, and its expression profile requires validation.

Mice

Pax7-IRES-CreERT2

Strain Name:C57BL/6Smoc-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200099

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

Il9-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il9em1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00023

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il9.

Mice

R26-CAG-LSL-FCGR3A-IRES-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem2(SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215052

SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the the Rosa26 locus.

Mice

Npr3-2A-DreERT2

Strain Name:C57BL/6Smoc-Npr3em1(2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190015

The 2A-DreERT2 cassette is inserted before 3'UTR region of Npr3 gene.

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