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Models

About 1,246 results
Mice

Pvalb-2A-mCherry

Strain Name：C57BL/6Smoc-Pvalbem(2A-mCherry)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220177

2A-mCherry expression cassette was knocked into the Pvalb gene stop codon site.

Mice

Notch1-CreERT2

Strain Name：C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200122
Validation Data：Presence

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

Il17f-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17fem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00031

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17f.

Mice

Lepr-RSR-CreERT2

Strain Name：C57BL/6Smoc-Leprtm1(rox-stop-rox-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210112

rox-stop-rox-CreERT2-WPRE-polyA expression cassette was knocked into the Lepr gene.

Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

Mice

Il17c-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210119
Validation Data：Presence

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

Clec4f-IRES-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Clec4fem1(IRES-iCre-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200069
Validation Data：Presence

A IRES-iCre-2A-tdTomato expression cassette was knocked into the Clec4f gene stop codon site.

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