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Models

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Mice

Scgb1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200129

A IRES-CreERT2 expression cassette was knocked into the Scgb1a1 gene stop codon site.

Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

Nphs2-CreERT2

Strain Name：C57BL/6Smoc-Nphs2tm1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00128

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

Il18-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00032

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

Mice

Foxp3-DreERT2

Strain Name：C57BL/6Smoc-Foxp3em5(IRES-DreER)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200198

A IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

R26-CAG-LSL-Gpld1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Gpld1-IRES-tdTomato-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210004

A CAG-LSL-Gpld1-IRES-tdTomato-Wpre-pA expression cassette was knocked into via.

Mice

Txlna-Luc-EGFP

Strain Name：C57BL/6Smoc-Txlnaem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00026

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Txlna.

Mice

Shh-CreERT2

Strain Name：C57BL/6Smoc-Shhem1(CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200145

A CreERT2-WPRE-polyA expression cassette was knocked into the Shh gene start codon site.

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