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Models

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Mice

Il16-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il16em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00028

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il16.

Mice

R26-CAG-LSL-PhiC31-ERT2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-STOP-Loxp-PhiC31-ERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-230051

CAG-Loxp-STOP-Loxp-PhiC31-ERT2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.

Mice

Glp1r-IRES-Cre

Strain Name：C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200134

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

hANGPTL3(3)

Strain Name：C57BL/6Smoc-Angptl3em2(hANGPTL3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210037

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.

Mice

Hopx-IRES-CreERT2

Strain Name：C57BL/6Smoc-Hopxem1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200136

A IRES-CreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

R26-CAG-LSL-hTM6SF2*E167K-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200017

These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Emx1-IRES-Cre

Strain Name：C57BL/6Smoc-emx1em1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200149

A IRES-Cre expression cassette was knocked into the Emx1 gene stop codon site.

Mice

Crbn-I391V/Rag2-KO

Strain Name：C57BL/6Smoc-Crbnem1(I391V)Rag2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210398

Crbn-I391V(NM-KI-200331) was crossed with Rag2-KO(NM-KO-190429) to generate Crbn-I391V/Rag2-KO mice.

Mice

R26-CAG-LNL-CaMPARI

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-CaMPARI)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00090

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven CaMPARI gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

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