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Mice

hPD-L1/hSIGLEC15

Strain Name:C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

Foxn1-IRES-Cre

Strain Name:C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Il17c-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

Cela1-2A-DreERT2

Strain Name:C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190094

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

Itgax-2A-DreERT2

Strain Name:C57BL/6Smoc-Itgaxem1(2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190032

A 2A-DreERT2 expression cassette was knocked into the Itgax gene stop codon site.

Mice

hIL18

Strain Name:C57BL/6Smoc-Il18tm1(hIL18)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210038

The endogenous mice Il18 gene was replaced by human IL18 gene.

Mice

hIL7R

Strain Name:C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State:Developing | Cat. NO.:NM-HU-210027

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

Mice

hPSGL-1(2)

Strain Name:C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210026

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

Txlna-Luc-EGFP

Strain Name:C57BL/6Smoc-Txlnaem1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00026

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Txlna.

Mice

H11-CAG-LSL-Mycn-IRES-EGFP

Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-HAtag-Mycn-IRES-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190084

These mice harbor a CAG-LSL-HA tag-Mycn-IRES-EGFP cassette in the lgs2 locus generated by homologous recombination.

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