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Models

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Mice

hLILRB4

Strain Name：C57BL/6Smoc-Lilrb4atm1(hLILRB4 )Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210024
Validation Data：Presence

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

R26-hCD46-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-hCD46-IRES-tdTomato-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190087
Validation Data：Presence

These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hPD-L1/hVEGFR2

Strain Name：C57BL/6Smoc-Cd274tm1(hCD274)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000102

hPD-L1(NM-HU-00062) was crossed with hKDR(NM-HU-00098) to generate hPD-L1/hKDR.

Mice

Dppa3-IRES-Cre

Strain Name：C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00040
Validation Data：Presence  |  Publications：1piece

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.

Mice

Slc17a7-IRES-Cre

Strain Name：C57BL/6Smoc-Slc17a7em1(IRES2-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200086
Validation Data：Presence

A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.

Mice

Trp63-DreERT2

Strain Name：C57BL/6Smoc-Trp63em1(DreERT2-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190029
Validation Data：Presence  |  Publications：1piece

A DreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene.

Mice

Agrp-IRES-Dre

Strain Name：C57BL/6Smoc-Agrpem(IRES-Dre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220330

IRES-Dre expression cassette was knocked into the Agrp gene stop codon site.

Mice

R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200257

A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.

Mice

Bhlha15-CreERT2

Strain Name：C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200080
Validation Data：Presence

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

Mice

hIL7R

Strain Name：C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210027
Validation Data：Presence

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

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