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Models

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Mice

R26-CAG-hFcRn

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00081

A human FCGRT expression cassette was knocked in mouse Rosa26 loci.

Mice

R26-SA-BirA

Strain Name：B6;129S-Gt(ROSA)26Sortm1(SA-BirA-V5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00085

A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally.

Mice

H11-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18009

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

Mice

H11-CAG-LSL-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190110

These mice harbor a CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA cassette in mouse H11 locus via homologous recombination.

Mice

R26-CAG-LSL-NgAgo-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NgAgo-IRES-EGFP-WPRE-pA)
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18011

These mice harbor a CAG-LSL-NgAgo-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18007

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

R26-TetO-Dre-IRES-mtagBFP2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-pA-Ins-Ins-TetO-Dre-IRES-BFP-pA-Ins-Ins)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190020

The SA-polyA-Ins-Ins-TetO-Dre-IRES-BFP-polyA-Ins-Ins cassette is inserted in mouse Rosa26 loci.

Mice

R26-SA-rtTA

Strain Name：B6;129S-Gt(ROSA)26Sortm1(SA-V5-M2rtTA-FRT-WPRE-FRT-polyA-attb-PGK-Neo-polyA-attp)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18025

These mice harbor a SA-V5-M2rtTA-FRT-WPRE-FRT-polyA-attb-PGK-Neo-polyA-attp expression cassette in mouse Rosa26 loci homologous recombination.

Mice

R26-CAG-LSL-dCas9-VPR-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18004

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

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