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Models

About 1,255 results
Mice

Cd274-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Cd274em1(Kozak-CreERT2-2A-tdTomato-wpre-pA)Smoc
Strain State：Developing | Cat. NO.：NM-KI-200289

Kozak-CreERT2-2A-tdTomato-wpre-pA expression cassette was knocked into the Cd274 gene start codon site via CRISPR/Cas9 mediated recombination.

Mice

Trpv2-Flox

Strain Name：B6;129S-Trpv2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00023

Mice homozygous for a knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.

Mice

Mir22-KO(FVB)

Strain Name：FVB-Mir22tmSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210396

These mice carry a knock-out mutation of Mir22 (microRNA 22)

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Gabra1-F324L

Strain Name：C57BL/6Smoc-Gabra1em(F324L)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-220099

These mice carry a F324L mutation of Gabra1 gene.

Mice

Ptpn2-Y278C

Strain Name：C57BL/6Smoc-Ptpn2tm(Y278C)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225038

These mice carry a Y278C mutation of Ptpn2 gene.

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19em1(hCD19)Cd3eem1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL6/hIL6R

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Il6raem1(hIL6R)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190025

This IL6 and IL6R double knockin strain is established by crossing IL6-HU and IL6R-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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