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Models

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Mice

Il34-Luc-2A-EGFP

Strain Name：B6;129S-Il34tm1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00035

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il34.

Mice

Atp1a1-2A-CreERT2

Strain Name：C57BL/6Smoc-Atp1a1em(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215079

2A-CreERT2 expression cassette was knocked into the Atp1a1 gene .

Mice

Il5-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il5em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00022

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il5.

Mice

Clec4f-2A-CreERT2

Strain Name：C57BL/6Smoc-Clec4fem(2A-CreERT2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225083
Validation Data：Presence

2A-CreERT2 expression cassette was knocked into the Clec4f gene .

Mice

hPD-1/hICOS(2)

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Icostm1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000100
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Mice

Sftpc-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sftpcem(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18020
Validation Data：Presence

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Sftpc gene via homologous recombination to establish a tamoxifen inducible Sftpc-CreERT2 tool stain. *This strain CreERT2 has leakage (see validation data for details), please select according to the purpose of the study。

Mice

Oprk1-2A-Cre

Strain Name：C57BL/6Smoc-Oprk1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200299
Validation Data：Presence

2A-Cre expression cassette was knocked into the Oprk1 gene stop codon site. Oprk1 (opioid receptor, kappa 1) encodes opioid receptor which was expressed in multiple brain regions. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids.

Mice

Clu-2A-DreERT2

Strain Name：C57BL/6Smoc-Cluem2(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200025
Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Clu gene stop codon site.

Mice

Cdkn2a-2A-DreERT2(p16-2A-DreERT2)

Strain Name：C57BL/6Smoc-Cdkn2aem(2A-DreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225086

2A-DreERT2 expression cassette was knocked into the stop codon of the Cdkn2a gene p16INK4a transcript.

Mice

Pbsn-2A-CreERT2

Strain Name：C57BL/6Smoc-Pbsnem1(V5-2A-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200190
Validation Data：Presence

A V5-2A-CreERT2-WPRE-polyA expression cassette was knocked into the Pbsn gene stop codon site.

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