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Mice

Il6-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il6em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00011

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il6.

Mice

Plin1-2A-DreERT2

Strain Name：C57BL/6Smoc-Plin1em1(2A-DreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190034

A 2A-DreERT2 expression cassette was knocked into the Plin1 gene stop codon site.

Mice

Nmu-2A-Cre

Strain Name：C57BL/6Smoc-Nmuem1(2A-Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200298

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.

Mice

Col1a2-2A-Cre

Strain Name：C57BL/6Smoc-Col1a2em1(2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215043

2A-Cre expression cassette was knocked into the Col1a2 gene.

Mice

hPD-L1/hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000099

hPD-L1(NM-HU-00062) was crossed with hSIRPA(2)(NM-HU-18015) to generate hPD-L1/hSIRPA(2).

Mice

Pgr-Cre

Strain Name：C57BL/6Smoc-Pgrem1(iCre-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200117

A iCre-WPRE-pA expression cassette was knocked into the Pgr gene start codon site.

Mice

Tnni3-dCreERT2

Strain Name：C57BL/6Smoc-Tnni3em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200014

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnni3 gene start codon site.

Mice

R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EGFR T790M-del19-luciferase-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190009

A SA-2xpolyA-CAG-LSL-EGFR(T790M-del19)-IRES-luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EGFR(T790M-del19) protein.

Mice

hPD-1/hICOS(2)

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Icosem1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000100

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Mice

Vip-IRES-Cre

Strain Name：C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200100

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.

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