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Models

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Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

Siglec1-Cre

Strain Name：C57BL/6Smoc-Siglec1em1(iCre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215032

iCre-polyA expression cassette was knocked into the Siglec1 gene.

Mice

Tafa2-V5-Flag

Strain Name：C57BL/6Smoc-Tafa2em1(V5-Flag)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200287

V5-Flag expression cassette was knocked into the Tafa2 gene stop codon site via CRISPR/Cas9 mediated recombination.

Mice

Il7r-Cre

Strain Name：C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200306

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

Mice

Il17c-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

hPD-L1/hSIGLEC15

Strain Name：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

Krt5-2A-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

Il17f-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17fem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00031

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17f.

Mice

Ly6a-2A-Cre

Strain Name：C57BL/6Smoc-Ly6aem1(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190028

A 2A-iCre expression cassette was knocked into the Ly6a gene stop codon site.

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