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Mice

Tigre-TetO-hEGFR*T790M/del19-IRES-GFP-2A-Cre

Strain Name：C57BL/6Smoc-Igs7em1(tetO-EGFR(T790M)-del19-IRES-GFP-2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200259

A tetO-EGFR(T790M)-del19-IRES-GFP-2A-Cre expression cassette was knocked into the TIGRE locus.

Mice

hIL17A/hIL17F

Strain Name：C57BL/6Smoc-Il17atm1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200281

The endogenous mouse Il17a&Il17f genes were replaced by human IL17A&IL17F gene.

Mice

Nphs2-CreERT2

Strain Name：C57BL/6Smoc-Nphs2tm1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00128

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

Mice

Wnt1-Dre

Strain Name：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200176

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

Mice

Cd19-2A-DreERT2

Strain Name：C57BL/6Smoc-Cd19em(2A-DreERT2-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215084

2A-DreERT2-Wpre-pA expression cassette was knocked into the Cd19 gene .

Mice

Tnnt2-dCreERT2

Strain Name：C57BL/6Smoc-Tnnt2em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200015

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnnt2 gene start codon site.

Mice

hPD-L1/hSIGLEC15

Strain Name：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Il17c-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

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