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Models

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Mice

Glp1r-IRES-Cre

Strain Name:C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200134
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

Ucp1-CreERT2

Strain Name:C57BL/6Smoc-Ucp1em1(Kozak-CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190102
Validation Data:Presence

A Kozak-CreERT2-WPRE-polyA expression cassette was knocked into the Ucp1 gene start codon site.

Mice

Avil-Cre

Strain Name:C57BL/6Smoc-Avilem1(Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-215036
Validation Data:Presence

Cre expression cassette was knocked into the Avil gene.

Mice

Calb2-IRES-Cre

Strain Name:C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200102
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

Hopx-IRES-CreERT2

Strain Name:C57BL/6Smoc-Hopxem1(IRES-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200136
Validation Data:Presence

A IRES-CreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

Rorc-2A-tdTomato-2A-DTR

Strain Name:C57BL/6Smoc-Rorcem(T2A-tdTomato-P2A-DTR)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-204991

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Rorc gene .

Mice

Foxn1-IRES-Cre

Strain Name:C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200106
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Cx3cr1-CreERT2

Strain Name:C57BL/6Smoc-Cx3cr1em1(creERT2-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200157
Validation Data:Presence

A creERT2-WPRE-polyA expression cassette was knocked into the Cx3cr1 gene start codon site.

Mice

Shh-CreERT2

Strain Name:C57BL/6Smoc-Shhem1(CreERT2-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200145
Validation Data:Presence

A CreERT2-WPRE-polyA expression cassette was knocked into the Shh gene start codon site.

Mice

Nkx2-1-CreERT2

Strain Name:C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200123
Validation Data:Presence

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

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