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Models

About 1,246 results
Mice

Ace2-2A-CreERT2

Strain Name:C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200187
Validation Data:Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

Alb-2A-DTRGFP(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-DTRGFP)Smoc
Strain State:Developing | Cat. NO.:NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name:C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18039
Validation Data:Presence  |  Publications:1piece

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

Aicda-Cre

Strain Name:C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200160
Validation Data:Presence

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

Lgr5-EGFP-IRES-CreERT2

Strain Name:C57BL/6Smoc-Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200154
Validation Data:Presence

A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site.

Mice

Cd19-Cre-IRES-tdTomato

Strain Name:C57BL/6Smoc-Cd19em1(iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200061
Validation Data:Presence

A iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA expression cassette was knocked into the Cd19 gene.

Mice

Alb-2A-HSVTK(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-HSVTK)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-215046

2A-HSVTK expression cassette was knocked into the Alb gene.

Mice

Csf1r-IRES-Cre

Strain Name:C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190026
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Csf1r gene stop codon site.

Mice

Mefv-hMEFV*V726A

Strain Name:C57BL/6Smoc-Mefvtm1(hMEFV-V726A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

Zbtb46-IRES-Cre

Strain Name:C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200096
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site.

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