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Mice

Kras-LSL-G12D

Strain Name：C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190003

exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name：C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18039

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

Ccr2-2A-DreERT2

Strain Name：C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200023

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.

Mice

Alb-2A-DTRGFP(NMG)

Strain Name：NOD-Prkdcscid Il2rgem1Albem1(2A-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

Adgre1-2A-CreERT2

Strain Name：C57BL/6Smoc-Adgre1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190025

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

Mice

Acadm-repeat(E8-10)

Strain Name：C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

Aicda-Cre

Strain Name：C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200160

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

Wnt5b-IRES-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Wnt5bem(IRES-CreERT2-P2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215083

IRES-CreERT2-P2A-tdTomato expression cassette was knocked into the Wnt5b gene .

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