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Models

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Mice

hIL18BP

Strain Name:C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210039

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Mice

hIL18

Strain Name:C57BL/6Smoc-Il18tm1(hIL18)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210038

The endogenous mice Il18 gene was replaced by human IL18 gene.

Mice

hIL7R

Strain Name:C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210027

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

Mice

hPSGL-1(2)

Strain Name:C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210026

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

hLILRB4

Strain Name:C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210024

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

R26-pAlb-TK-IRES-Luc-2A-EGFP(NOD-scid)

Strain Name:NOD-PrkdcscidGt(ROSA)26Sorem1(Alb-TK-IRES-luc-2A-EGFP-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18040

These Nod-Scid mice harbor a cassette containing Alb promoter-TK-IRES-luciferase-2A-EGFP-polyA. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name:C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

Alb-CreERT2

Strain Name:B6.129S-Albtm1.1(CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00002

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.

Mice

KPC(2)

Strain Name:C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-220014

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

Mycn-TRE-EGFP

Strain Name:B6;129S-Mycntm1(TRE-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00008

A TRE site and a loxp EGFP casette were inserted into introns 1-2 to create a Dox-inducible N-myc gene silence mice.

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