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Models

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Mice

hIL5-Tg(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Tg(hIL5)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-215005

These transgenic mice carry humanized IL5.

Mice

hIL34-Tg(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Tg(hIL34)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-220431
Validation Data:Presence

These transgenic mice carry humanized IL34.

Mice

hIL6-Tg(NMG)

Strain Name:NOD-PrkdcscidIl2rgem1Tg(hIL6)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210140

These transgenic mice carry humanized IL6.

Mice

R26-pAlb-TK-IRES-Luc-2A-EGFP(NOD-scid)

Strain Name:NOD-PrkdcscidGt(ROSA)26Sorem1(Alb-TK-IRES-luc-2A-EGFP-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18040

These Nod-Scid mice harbor a cassette containing Alb promoter-TK-IRES-luciferase-2A-EGFP-polyA. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name:C57BL/6Smoc-Lyz2tm3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

Alb-CreERT2

Strain Name:B6.129S-Albtm1.1(CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00002
Validation Data:Presence  |  Publications:1piece

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.

Mice

KPC(2)

Strain Name:C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-220014

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

Mycn-TRE-EGFP

Strain Name:B6;129S-Mycntm1(TRE-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00008

A TRE site and a loxp EGFP casette were inserted into introns 1-2 to create a Dox-inducible N-myc gene silence mice.

Mice

Isl1-CreERT2

Strain Name:C57BL/6Smoc-Isl1em1(CreERT2) Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00013
Validation Data:Presence  |  Publications:1piece

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Mice

a-IRES-Cre

Strain Name:C57BL/6Smoc-atm1(Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200027
Publications:1piece

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

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