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Models

About 1,246 results
Mice

R26-SA-BirA

Strain Name:B6;129S-Gt(ROSA)26Sortm1(SA-BirA-V5)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00085
Validation Data:Presence

A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally.

Mice

hFCRN

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-hFcRn)Fcgrtem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00109
Validation Data:Presence  |  Publications:1piece

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032)mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

H11-CAG-ddCre

Strain Name:C57BL/6Smoc-Igs2em1(CAG-ddCre-V5-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00086

These H11-(CAG-ddCre-V5-polyA) mice are established by knocking CAG-LSL-ddCre-V5-polyA conditional expression cassette in mouse H11 loci.

Mice

R26-CAG-LSL-Cas9-IRES-Luc

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Cas9-IRES-Luciferase-pA)
Strain State:Repository Live | Cat. NO.:NM-KI-18002

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.

Mice

hIL21R

Strain Name:C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210031
Validation Data:Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

hIL4-Tg(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-215004
Validation Data:Presence

These transgenic mice carry humanized IL4.

Mice

hIL15-Tg(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Tg(hIL15)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210141
Validation Data:Presence

These transgenic mice harbor hIL15 expression cassettes.

Mice

hIL3-hCSF2-Tg(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-215006
Validation Data:Presence

These transgenic mice carry humanized IL3 and humanized CSF2.

Mice

Cd8a-IRES-DTRGFP/Cd8a-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Cd8aem2(IRES-DTREGFP)Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210399

Cd8a-IRES-DTRGFP(NM-KI-190045) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate Cd8a-IRES-DTRGFP/Cd8a-IRES-luc-2A-EGFP mice.

Mice

R26-CAG-LSL-RSR-tdTomato-2A-DTR

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-RSR-tdTomato-2A-DTR)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190086
Validation Data:Presence  |  Publications:2piece

These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.