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Models

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Mice

R26-SA-BirA

Strain Name：B6;129S-Gt(ROSA)26Sortm1(SA-BirA-V5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00085

A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

H11-CAG-ddCre

Strain Name：C57BL/6Smoc-Igs2em1(CAG-ddCre-V5-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00086

These H11-(CAG-ddCre-V5-polyA) mice are established by knocking CAG-LSL-ddCre-V5-polyA conditional expression cassette in mouse H11 loci.

Mice

hIL15-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL15)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210141

These transgenic mice harbor hIL15 expression cassettes.

Mice

hIL4-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215004

These transgenic mice carry humanized IL4.

Mice

hIL3-hCSF2-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215006

These transgenic mice carry humanized IL3 and humanized CSF2.

Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

R26-CAG-LSL-Itpr1-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-Itpr1-3xFlag-IRES-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18046

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Itpr1-3xFlag-IRES-tdTomato expression cassette. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.

Mice

R26-CAG-LSL-Alkbh5-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Alkbh5-3xFLAG-IRES-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190054

These mice harbor a CAG-LSL-Alkbh5-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

Tpk1-Flox

Strain Name：C57BL/6Smoc-Tpk1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2110060

These mice carry loxP sites flanking exon 4 of Tpk1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tpk1 gene.

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