Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001
Validation Data：Presence
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Publications：59piece
Prkdc and Il2rg genes were both knocked-out in NOD mice.
Lacking mature T, B and NK cells;
Low immune rejection against human cells and tissues;
Good tumorigenicity so that a small number of cells can form tumors;
Significant improvement in the survival of transplanted human cells and tissues;
Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models;
Suitable as the carrier mice for the transplantation of heterologous cells and tissues.
