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Models

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Mice

Clec1b-KO

Strain Name：C57BL/6Smoc-Clec1bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190229

This Clec1b knockout mouse model was generated by knocking out the exon2-4 region of the Clec1b.

Mice

Ccl4-KO

Strain Name：C57BL/6Smoc-Ccl4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190016

This Ccl4 knockout mouse model was generated by knocking out the exon 2 region of the Ccl4 .

Mice

Clec12a-KO

Strain Name：C57BL/6Smoc-Clec12aem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190222

This Clec12a knockout mouse model was generated by knocking out the exon2-4 region of the Clec12a.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Il4ra-KO

Strain Name：C57BL/6Smoc-Il4raem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190504

Exon 4 of Il4ra gene was deleted to generate Il4ra knockout mice.

Mice

Ighm/Ighd-KO

Strain Name：C57BL/6Smoc-Ighmem1Ighdem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200610

Exon 1-6 of Ighm and exon 1-5 of Ighd gene was deleted to generate Ighm and Ighd knockout mice. Homozygous mutant mice lack mature B cells. It may be useful as a model for B cell immunodeficiency found in humans.

Mice

B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-002

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

H2/H2-K1-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1h2em2H2-K1em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-006

Exon 2 of H2;H2-K1 gene was deleted to generate H2;H2-K1 knockout mice.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.  These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Pd-1-KO

Strain Name：C57BL/6Smoc-Pdcd1em3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190423

The Pdcd1 knockout mouse model was generated by knocking out the exon2-4 region of the Pdcd1.

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