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Models

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Mice

hIL6/hIL6R

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Il6raem1(hIL6R)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190025

This IL6 and IL6R double knockin strain is established by crossing IL6-HU and IL6R-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Il1f8-KO

Strain Name：C57BL/6Smoc-Il1f8em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190478

Exon 4 of Il1f8 gene was deleted to generate Il1f8 knockout mice.

Mice

hPVR

Strain Name：C57BL/6Smoc-Pvrtm1(hPVR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190012

The endogenous mouse Pvr gene was replaced by human PVR gene.

Mice

Ighj-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Ighjem4Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200582

Ighj gene was deleted to generate Ighj knockout mice.

Mice

hAPOE2

Strain Name：C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190013

This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.

Mice

Igl-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Iglem4Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200583

Igl gene was deleted to generate Igl knockout mice.

Mice

hHER2

Strain Name：C57BL/6Smoc-Erbb2tm1(hERBB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200115

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

Mice

Cd200-KO

Strain Name：C57BL/6Smoc-Cd200em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

Ifnar1-KO

Strain Name：C57BL/6Smoc-Ifnar1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18038

The Ifnar1 knockout mouse model was obtained by knocking out the exon 3-11 region of mouse Ifnar1 gene.

Mice

Drd2-KO

Strain Name：C57BL/6Smoc-Drd2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190265

This Drd2 knockout mouse model was generated by knocking out the exon 3 region of the Drd2.

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