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Models

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Mice

Btk-KO

Strain Name：C57BL/6Smoc-Btkem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190005

This Btk knockout mouse model was generated by deleting the Exon 4-5 region of the Btk .

Mice

Cd4-KO(2)

Strain Name：C57BL/6Smoc-Cd4em3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190441

Cd4-KO(2) mice (Stock No.NM-KO-190441） carry a knockout allele derived from the targeted deletion of exon 3-8. While Cd4-KO mice (Stock No.NM-KO-18023) have been pulled from shelves for some reasons.

Mice

Nfe2l2-Flox

Strain Name：C57BL/6Smoc-Nfe2l2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200198

These mice carry loxP sites flanking exon 5 of Nfe2l2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nfe2l2 gene.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

Il12b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00025

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

Il17a-2A-CreERT2

Strain Name：C57BL/6Smoc-Il17aem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00059

A 2A-Cre cassette was inserted before stop codon of mouse Il17a gene which is known as a T cell marker.

Mice

Il1a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00009

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

Il12a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00024

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il12a.

Mice

Il11-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il11em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00036

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il11.

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