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Models

About 95 results
Mice

Dna2-KO

Strain Name：C57BL/6Smoc-Dna2em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-250724

The exon 4-7 of Dna2 gene was deleted to generate Dna2 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Slc4a1-KO

Strain Name：C57BL/6Smoc-Slc4a1em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-242564

The exon 2-20 of Slc4a1 gene was deleted to generate Slc4a1 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

hTIGIT(BALB/c,3)

Strain Name：C.B6-Tigittm3(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-234664

The hTIGIT(3)(NM-HU-200244) mice were backcrossed to BALB/c genetic background, to create the new strain of hTIGIT(BALB/c,3)(NM-HU-234664) mice.

Mice

hPD-L1(BALB/c,E3-4)

Strain Name：BALB/cAnSmoc-Cd274em2(hPD-L1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-230474

The hPD-L1(2)(NM-HU-190039) mice were backcrossed to BALB/c genetic background, to create the new strain of hPD-L1(BALB/c,2)(NM-HU-230474) mice.

Mice

h4-1BB(BALB/c,2)

Strain Name：C.B6-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-234662

The h4-1BB(2)(NM-HU-190077) mice were backcrossed to BALB/c genetic background, to create the new strain of h4-1BB(BALB/c,2) (NM-HU-234662) mice.

Mice

B2m-KO(NMG,2)

Strain Name：NOD-PrkdcscidIl2rgem1B2memSmoc
Strain State：Developing | Cat. NO.：NM-KO-220540

The B2m-KO(NOD-scid)(NM-KO-18035) mice were backcrossed to NMG genetic background, to create the new strain of B2m-KO(NMG,2)(NM-KO-220540) mice.

Mice

Ahr-KO

Strain Name：C57BL/6Smoc-Ahrem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18008

Exon3 of Ahr gene was deleted to generate Ahr knockout mice. The homozygous female mice of this strain had impaired fertility. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.  These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC Class II(I-A/I-E)-KO(Nod-Scid)

Strain Name：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-18057

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

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