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Models

About 95 results
Mice

MHCII/B2m-KO(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State:Repository Live | Cat. NO.:NM-NSG-014

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

Mice

C57BL/6

Strain Name:C57BL/6Smoc
Strain State:Repository Live | Cat. NO.:SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Il9r-KO

Strain Name:C57BL/6Smoc-Il9rem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190511

Exon 3-7 of Il9r gene was deleted to generate Il9r knockout mice.

Mice

Slc6a1-S295L

Strain Name:C57BL/6Smoc-Slc6a1em2(S295L)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190014

These mice carry a p.S295L mutation in Slc6a1 gene .

Mice

R26-CAG-LSL-GiDREADD(hM4Di)-2A-mCitrine

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190093

These mice harbor a CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-GqDREADD(hM3Dq)-2A-mCitrine

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GqDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190106

These mice harbor a CAG-LSL-HA-GiDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Cells

HCC1937

Strain Name:HCC1937
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-R08

The HCC1937 cell line is derived initially from the mammary gland of a 23-year-old Caucasian female with breast carcinoma that is associated with genetic predisposition.

Literature

Genetic Targeting of Organ-Specific Blood Vessels

Model Organisms:小鼠 Product & Service:Nrg1-CrexER, Nrg1-CreER, Wt1-CrexER, Tie2-Dre, Mfsd2a-CrexER Research field:Cardiovascular

血管生成 心脏

Literature

Genetic Lineage Tracing of Non-Myocyte Population by Dual Recombinases.

Model Organisms:小鼠 Product & Service:Isl1-CreER, Vim-CreER, PostnCreER, R26-DreER, Tnnt2-Dre, Tnni3-Dre, IR1, IR3, NR1 Research field:Heart

心脏发育 遗传谱系示踪 DeaLT

Literature

Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes

Model Organisms:小鼠 Product & Service:Kit-CreER Research field:Heart

遗传谱系示踪 心脏干细胞

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